bis(7)-Tacrine

Product Name: bis(7)-Tacrine
Synonyms: N,N-bis(1,2,3,4-tetrahydro-9-acridinyl)-1,7-heptanediamine, dihydrochloride 1,7-N-heptylene-bis-9,9-amino-1,2,3,4-tetrahydro-acridineMedchemexpress.com
Product Overview: A tacrine dimer, linked via a 7-carbon alkyl spacer; inhibits AChE (IC50 = 0.40 nM), making it more than 1,000 times more potent than tacrine ;protects against hydrogen peroxide induced apoptosis in rat pheochromocytoma cellsTacrine is an amino acridine c
Shipping: wet ice
CAS NO: 1693758-51-8 IPI549
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C33H40N4 • 2HCl
SMILES: [H]N(CCCCCCCN([H])C1=C(C=CC=C2)C2=NC3=C1CCCC3)C4=C5C(C=CC=C5)=NC6=C4CCCC6.Cl.ClAutophagy inhibitors
Molecular Weight: 565.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/12/1525