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2, 4’-DDE-d8

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Product Name : 2, 4’-DDE-d8Description:Product informationCAS: 1402834-57-4Molecular Weight:326.07Formula: C14H8Cl4Chemical Name: 1-chloro-4-{2,2-dichloro-1-ethenyl}(²H₄)benzeneSmiles : C1=C(C(C2=C(Cl)C()=C()C()=C2)=C(Cl)Cl)C()=C()C(Cl)=C1InChiKey: ZDYJWDIWLRZXDB-PGRXLJNUSA-NInChi...
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BD1063-d8 dihydrochloride

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Product Name : BD1063-d8 dihydrochlorideDescription:Product informationCAS: 1246819-69-1Molecular Weight:281.25Formula: C13H18Cl2N2Chemical Name: 1--4-methyl(²H₈)piperazineSmiles : C1()N(C)C()()C()()N(CCC2=CC(Cl)=C(Cl)C=C2)C1()InChiKey: SUIZRDJCBVPASY-COMRDEPKSA-NInChi...
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Icariin

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Product Name : IcariinSynonym: 4′-O-Methyl-8-γ,γ-dimethylallylkaempferol-3-rhamnoside-7-glucoside , IearilineCAS : 489-32-7Molecular formula:C33H40O15Molecular Weight : 676.{{2444815-84-1} site|{2444815-84-1}...
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Coumarine 334

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Product Name : Coumarine 334Synonym: C334, Coumarin 521, NSC 369287, 5-Acetyl-3-oxa-13-azatetracycloheptadeca-1,5,7,9(17)-tetraen-4-oneCAS : 55804-67-6Molecular formula:C17H17NO3Molecular...
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BCECF acid

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Product Name : BCECF acidSynonym: 2′,7′-Bis(carboxyethyl)-5(6)-carboxyfluoresceinCAS : 85138-49-4Molecular formula:C27H20O11Molecular Weight : 520.{{1609392-27-9} site|{1609392-27-9} Protocol|{1609392-27-9}...
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6-SFX

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Product Name : 6-SFXSynonym: 6-FAM-X , Fluorescein-6-carboxamidocaproic acid , 6-(Fluorescein-6-carboxamido)hexanoic acidCAS : 323196-16-3Molecular formula:C27H23NO8Molecular...
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Cyamemazine-d6

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Product Name : Cyamemazine-d6Description:Product informationCAS: 1216608-24-0Molecular Weight:329.49Formula: C19H21N3SChemical Name: 10-{3--2-methylpropyl}-10H-phenothiazine-2-carbonitrileSmiles : C()()N(CC(C)CN1C2=CC(=CC=C2SC2=CC=CC=C12)C#N)C()()InChiKey: SLFGIOIONGJGRT-XERRXZQWSA-NInChi :...
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Bisoprolol-d5

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Product Name : Bisoprolol-d5Description:Product informationCAS: 1189881-87-5Molecular Weight:330.47Formula: C18H31NO4Chemical Name: 1--3-(4-{methyl}phenoxy)(²H₅)propan-2-olSmiles : C()(OC1=CC=C(COCCOC(C)C)C=C1)C()(O)C()()NC(C)CInChiKey: VHYCDWMUTMEGQY-FFNOJTKMSA-NInChi :...
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Fmoc-Glu(OtBu)-Ser(psi(Me, Me)pro)-OH

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Product Name : Fmoc-Glu(OtBu)-Ser(psi(Me, Me)pro)-OHDescription:Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide.CAS: 909115-33-9Molecular Weight:552.62Formula: C30H36N2O8Chemical Name: (4S)-3-carbonyl}amino)-5-oxopentanoyl]-2,2-dimethyl-1,3-oxazolidine-4-carboxylic acidSmiles...
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2′, 3′-Di-O-acetylguanosine

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Product Name : 2′, 3′-Di-O-acetylguanosineDescription:2′,3′-Di-O-acetylguanosine is a nucleoside analog.CAS: 42167-65-7Molecular Weight:367.31Formula: C14H17N5O7Chemical Name: (2R,3R,4R,5R)-4-(acetyloxy)-2-(2-amino-6-oxo-6,9-dihydro-3H-purin-9-yl)-5-(hydroxymethyl)oxolan-3-yl...
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Rheumone B

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Product Name : Rheumone BDescription:Rheumone B possesses antioxidant activity.CAS: 2095596-67-9Molecular Weight:448.42Formula: C22H24O10Chemical Name: 11-hydroxy-8-methoxy-4-methyl-10-{[(2S,...
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M2I-1

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Product Name : M2I-1Description:M2I-1 a small Mad2 inhibitor-1.CAS: 312271-03-7Molecular Weight:404.48Formula: C19H24N4O4SChemical Name: 5-(4-(Diisobutylamino)-3-nitrobenzylidene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dioneSmiles :...
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4-Chloro Perazine-d8

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Product Name : 4-Chloro Perazine-d8Description:Product informationCAS: 1346600-16-5Molecular Weight:381.99Formula: C20H24ClN3SChemical Name: 4-chloro-10-{3-propyl}-10H-phenothiazineSmiles : C1()N(C)C()()C()()N(CCCN2C3=CC=CC(Cl)=C3SC3=CC=CC=C23)C1()InChiKey: FRPMPGQTRXUECE-DHNBGMNGSA-NInChi...
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Lignoceric acid-d47

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Product Name : Lignoceric acid-d47Description:Product informationCAS: 68060-00-4Molecular Weight:415.93Formula: C24H48O2Chemical Name: (²H₄₇)tetracosanoic acidSmiles : C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C()()C(O)=OInChiKey:...
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4-Desfluoro-4-[4-(2-Oxo-2, 3-dihydro-1H-benzimidazol-1-yl)-3, 6-dihydropyridin-1(2H)-yl] Droperidol-d4

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Product Name : 4-Desfluoro-4- Droperidol-d4Description:Product informationCAS: 1346604-49-6Molecular Weight:578.70Formula: C34H34N6O3Chemical Name: 1-butanoyl}phenyl)-1,2,3,6-tetrahydropyridin-4-yl]-2,3-dihydro(4,5,6,7-²H₄)-1H-1,3-benzodiazol-2-oneSmiles :...
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2H-2-Ethyl-d5 Candesartan

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Product Name : 2H-2-Ethyl-d5 CandesartanDescription:Product informationCAS: 1246820-58-5Molecular Weight:473.54Formula: C26H24N6O3Chemical Name: 2-ethoxy-1--2H-1,2,3,4-tetrazol-5-yl}--4-yl)methyl]-1H-1,3-benzodiazole-7-carboxylic acidSmiles : C()()C()()N1N=NC(=N1)C1=CC=CC=C1C1C=CC(CN2C3C(=CC=CC=3N=C2OCC)C(O)=O)=CC=1InChiKey:...
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Palmitoylcarnitine

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Product Name : PalmitoylcarnitineDescription:Palmitoylcarnitine is an endogenous metabolite.CAS: 1935-18-8Molecular Weight:399.61Formula: C23H45NO4Chemical Name: 3-(hexadecanoyloxy)-4-(trimethylazaniumyl)butanoateSmiles :...
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rel-(R)-6-((R)-(2-Ethoxyphenoxy)(phenyl)methyl)morpholin-3-one-d5

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Product Name : rel-(R)-6-((R)-(2-Ethoxyphenoxy)(phenyl)methyl)morpholin-3-one-d5Description:Product informationCAS: 1292840-26-6Molecular Weight:332.41Formula: C19H21NO4Chemical Name: (6R)-6-phenoxy}(phenyl)methyl]morpholin-3-oneSmiles : C()()C()()OC1=CC=CC=C1O(1CNC(=O)CO1)C1C=CC=CC=1InChiKey: BXLPJKGEJVAHON-CBXZRGHLSA-NInChi :...
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Clenproperol

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Product Name : ClenproperolDescription:Clenproperol is a β2-adrenergic agonist.CAS: 38339-11-6Molecular Weight:263.16Formula: C11H16Cl2N2OChemical Name: 1-(4-amino-3,5-dichlorophenyl)-2-ethan-1-olSmiles :...
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EM 163

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Product Name : EM 163Description:Product informationCAS: 1206480-93-4Molecular Weight:849.88Formula: C44H60IN5O4Chemical Name: 1-Methyl-2, 5-bis(3-phenylpropyl)amino]carbonyl]pyridinium iodideSmiles :...
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T 0156 hydrochloride

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Product Name : T 0156 hydrochlorideDescription:Product informationCAS: 324572-93-2Molecular Weight:620.05Formula: C31H30ClN5O7Chemical Name: methyl 2--1-oxo-8--4-(3,4,5-trimethoxyphenyl)-1,2-dihydro-2,7-naphthyridine-3-carboxylate hydrochlorideSmiles...
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PSB 06126

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Product Name : PSB 06126Description:Product informationCAS: 1052089-16-3Molecular Weight:466.44Formula: C24H15N2NaO5SChemical Name: sodium 1-amino-4--9,10-dioxo-9,10-dihydroanthracene-2-sulfonateSmiles : .NC1C2=C(C(=CC=1S()(=O)=O)NC1=CC=CC3=CC=CC=C31)C(=O)C1=CC=CC=C1C2=OInChiKey:...
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β-Cyclodextrin, 98%

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Product Name : β-Cyclodextrin, 98%Synonym: IUPAC Name : 5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclononatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecolCAS NO.Metolazone :7585-39-9Molecular Weight :...
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(47.five ) 21 (52.five ) 16 (40.0 ) 24 (60.0 ) 29 (72.5 ) 11 (27.five ) six (15.0 ) 34 (85.0 ) 26 (65.0 ) 14 (35.0 ) 38 (95.0 ) two (five.0 ) 0.7 0.3.two 25 1122 24 750 0.7 0.4.0.0.0.0.0.0.0.196 (77.8 ) 56 (22.two ) 145 (57.5 ) 107 (42.5 ) 175 (69.four ) 77 (30.6 ) 219 (86.9 ) 33 (13.1 ) 26 (ten.3 ) 226 (89.7 ) 183 (72.6 ) 69 (27.four ) 148 (58.7 ) 104 (41.three ) 0.7 0.25.9 24 1166 24 764 0.7 0.2.170 (80.2 ) 42 (19.eight ) 126 (59.4 ) 86 (40.six ) 159 (75.0 ) 53 (25.0 ) 190 (89.6 ) 22 (ten.four ) 20 (9.four ) 192 (90.6 ) 157 (74.1 ) 55 (25.9 ) 110 (51.9 ) 102 (48.1 ) 0.7 0.25.9 24 11.0066.00 25 864 0.7 0.2.0.0.0.0.0.0.0.0.0.0.0.2014 The Authors. Cancer Medicine published by John Wiley Sons Ltd.P.

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(47.five ) 21 (52.5 ) 16 (40.0 ) 24 (60.0 ) 29 (72.5 )...
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) 17,798 (46.five ) 408 (1.1 ) four,625 (12.5 ) 31,945 (86.4 ) 9,674 (26.2 ) 9,331 (25.2 ) 17,973 (48.6 ) 24,257 (65.six ) five,458 (14.eight ) 3,027 (8.2 ) 2,303 (six.2 ) 676 (1.eight ) 161 (0.4 ) six,594 (17.8 ) 1,249 (3.4 ) Guys N=458,331 54.7 (14.five) 47,808 (ten.4 ) 34,232 (7.5 ) 41,576 (9.1 ) 271,042 (59.1 ) 63,673 (13.9 ) 329,929 (72.six ) 254,991 (55.6 ) 32,069 (7.0 ) 273,674 (59.7 ) 152,588 (33.3 ) 644; 1; 0.0001 99,485 (21.7 ) 105,951 (23.1 ) 252,895 (55.two ) 216,663 (47.3 ) 34,252 (7.five ) 16,057 (three.5 ) 17,416 (3.8 ) three,133 (0.7 ) 1,227 (0.three ) 104,416 (22.eight ) 20,403 (four.five ) 4 600; 1; 0.0001 two,464; 1; 0.0001 2025; 1; 0.0001 528; 1; 0.0001 587; 1; 0.0001 34; 1; 0.0001 482; 1; 0.0001 94; 11; 0.0001 Statistics 2 or t; DF; p 174; 46,321; 0.0001 29,233; 1; 0.862; 1; 0.0001 1,151; 1; 0.0001 41,275; 1; 0.JGIMBernardy et al.: Gender

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) 17,798 (46.5 ) 408 (1.1 ) four,625 (12.five ) 31,945 (86.4 ) 9,674...
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Ression(S11).Inhumans,STATmutations resultinrelativeGHinsensitivityandgrowthretardation(32).GH alsoinducesearlyresponsegenesthatprecedecellgrowthanddifferentiationsignals(33)mediatedbyCCAATenhancer inding proteinandserumresponseelementsitesonthec-fospromoter.TheGHRmayalsotranslocatetothenucleusbytheimportin

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Ression(S11).Inhumans,STATmutations resultinrelativeGHinsensitivityandgrowthretardation(32).GH alsoinducesearlyresponsegenesthatprecedecellgrowthanddifferentiationsignals(33)mediatedbyCCAATenhancer inding proteinandserumresponseelementsitesonthec-fospromoter.TheGHRmayalsotranslocatetothenucleusbytheimportin /pathwayinconjunctionwithcoactivatoractivator(CoAA). Genetargetsfornuclear-mediatedGHRactionarepredominantlyproproliferative.ForcedGHRtargetingtothecellnucleus alsoenhancescellproliferationandtransformationresponsivenesstoautocrine-derivedGH.Therefore,CoAAandactivatedSTAT5 arebothrequiredforGH-dependentproproliferativeactionsof nuclearGHR(34). STAT5b mediates sexually dimorphic...
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APPRRSSIRNA KAP2_92_104SRFNRRVSVCAET SCN7A_898_910KNGCRRGSSLGQI REL_260_272KMQLRRPSDQEVS RS6_228_240IAKRRRLSSLRAS NMDZ

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APPRRSSIRNA KAP2_92_104SRFNRRVSVCAET SCN7A_898_910KNGCRRGSSLGQI REL_260_272KMQLRRPSDQEVS RS6_228_240IAKRRRLSSLRAS NMDZ1_890_902SFKRRRSSKDTST ADRB2_338_350ELLCLRRSSLKAY KPB1_1011_1023QVEFRRLSISAES ART_025_CXGLRRWSLGGLRRWSLGLRRWSLGGLRRWSL CAC1C_1974_1986ASLGRRASFHLEC CREB1_126_138EILSRRPSYRKIL LIPS_944_956GFHPRRSSQGATQ VTNC_390_402NQNSRRPSRATWL PTK6_436_448ALRERLSSFTSYE...
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0.039 0.040 0.041 0.041 0.042 0.042 0.042 0.042 0.042 0.043 0.043 0.043 0.044 0.045 0.045 0.045 0.046 0.046 0.047 0.047 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 0.491 Cell Death and DiseasePreclinical drug screening using Vk*MYC myeloma GM

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0.039 0.040 0.041 0.041 0.042 0.042 0.042 0.042 0.042 0.043 0.043 0.043 0.044 0.045...