Product Name: Zaragozic Acid A
Synonyms: (7S)-11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate]-2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-L-erythro-L-glycero-D-altro-7-trideculo-7,4-furanosonic acid Web Site click
Product Overview: A reversible competitive inhibitor of squalene synthase (Ki = 78 pM in vitro); reduces cholesterol synthesis in HepG2 cells (IC50 = 6 µM) and inhibits hepatic cholesterol synthesis in mice (ED50 = 0.2 mg/kg); also inhibits FPTase and GGPTase-I (IC50
Shipping: wet ice
CAS NO: 1223403-58-4 Product: LOXO-101
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C35H46O14
SMILES: O[C@@H]1[C@@H](OC(/C=C/[C@@H](C)C[C@@H](C)CC)=O)[C@]2(C(O)=O)[C@](O)(C(O)=O)[C@@H](C(O)=O)O[C@]1(O2)CCC([C@@H](OC(C)=O)[C@H](C)CC3=CC=CC=C3)=CPolo-like Kinase PLK) inhibitors
Molecular Weight: 690.7
Formulation: A white to light tan solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/7/3305.abstract
