XL019
XL019

XL019

Product Name: XL019
Synonyms: (2S)-N-[4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamideWeb Site:Medchemexpress
Product Overview: A potent, bioavailable JAK inhibitor with preference for JAK2 (IC50 = 2 nM) over JAK1 and JAK3 (IC50s = 130 and 250 nM, respectively); effective against JAK2V617F as well as JAK2 and inhibits phosphorylation of STAT5 in vivoJanus-associated kinases (JAKs)
Shipping: wet ice
CAS NO: 1161233-85-7 Product: BTZ043
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C25H28N6O2
SMILES: O=C([[email protected]]1NCCC1)NC(C=C2)=CC=C2C3=CC=NC(NC(C=C4)=CC=C4N5CCOCC5)=N3NO Synthase inhibitors
Molecular Weight: 444.5
Formulation: A crystalline solid
Purity: ≥90%PubMed ID:http://aac.asm.org/content/55/8/3691.abstract