Verubecestat
Verubecestat

Verubecestat

Product Name: Verubecestat
Synonyms: N-[3-[(5R)-3-amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide MK-8931Web Site click
Product Overview: An inhibitor of BACE1 and BACE2 (Kis = 2.2 and 0.38 nM, respectively)Verubecestat is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) and BACE2 (Kis = 2.2 and 0.38 nM, respectively). It has a high selectivity for BACE1 and
Shipping: dry ice
CAS NO: 1047634-63-8 Product: GSK2110183
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C17H17F2N5O3S
SMILES: FC1=CN=C(C(NC2=CC([[email protected]]3(C)CS(N(C)C(N)=N3)(=O)=O)=C(F)C=C2)=O)C=C1Saccharides and Glycosides inhibitors
Molecular Weight: 409.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/48/3/809.abstract