Product Name: VX-702
Synonyms: 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamideMedchemexpress
Product Overview: A third generation inhibitor of p38 MAP kinases, binding to both p38α and p38β (Kd = 3.7 and 17 nM, respectively); inhibits IL-6, IL-1β, and TNF-α production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml, respectively
Shipping: wet ice
CAS NO: 122795-43-1 Gadodiamide (hydrate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H12F4N4O2
SMILES: FC1=CC=CC(F)=C1N(C2=NC(C3=C(F)C=C(F)C=C3)=C(C(N)=O)C=C2)C(N)=OMembrane_Transporter/Ion_Channel_Compound_Library inhibitors
Molecular Weight: 404.3
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://www.bloodjournal.org/content/129/25/3332