VE-821
VE-821

VE-821

Product Name: VE-821
Synonyms: 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-2-pyrazinecarboxamide ATR Inhibitor IVWeb Site:Medchemexpress
Product Overview: An ATP-competitive inhibitor of ATR (IC50 = 26 nM); augments DNA damage and cell death of cancer cells in response to radiation under normal and hypoxic conditions; sensitizes cancer cells to chemotherapyAtaxia-telangiectasia and Rad3-related protein (ATR
Shipping: wet ice
CAS NO: 1108743-60-7 Entrectinib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H16N4O3S
SMILES: O=C(C1=NC(C2=CC=C(S(C)(=O)=O)C=C2)=CN=C1N)NC3=CC=CC=C3Gli inhibitors
Molecular Weight: 368.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/130/1/4