Tubastatin A (trifluoroacetate salt)

Product Name: Tubastatin A (trifluoroacetate salt)
Synonyms: N-hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]-benzamide, 2,2,2-trifluoroacetateMedchemexpress.com
Product Overview: Potent HDAC6 inhibitor (IC50 = 15 nM) with 1,000-fold selectivity against all other HDAC isoforms (IC50s >16 μM), excluding HDAC8 (IC50 = 0.9 μM); induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures; displays
Shipping: wet ice
CAS NO: 1421373-66-1 AZD-9291 (mesylate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H21N3O2 • CF3COOH
SMILES: CN(C1)CCC2=C1C3=C(N2CC4=CC=C(C(NO)=O)C=C4)C=CC=C3.FC(F)(C(O)=O)FATGL inhibitors
Molecular Weight: 449.4
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://www.bloodjournal.org/content/127/5/558