Temsirolimus
Temsirolimus

Temsirolimus

Product Name: Temsirolimus
Synonyms: 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate] rapamycin CCI-779 Web Site click
Product Overview: A dihydroxymethyl propionic acid ester of rapamycin with improved solubility that specifically inhibits mTOR signaling with a potency similar to that of rapamycin; demonstrates cytostatic activity in various mouse models of human tumors, including gliobla
Shipping: wet ice
CAS NO: 1234015-54-3 LY2606368 (dihydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C56H87NO16
SMILES: O=C(O[[email protected]](CC([[email protected]](C)/C=C(C)/[[email protected]@H](O)[[email protected]@H](OC)C([[email protected]@H](C1)C)=O)=O)([H])[[email protected]](C)C[[email protected]@H]2CC[[email protected]@H](OC(C(C)(CO)CO)=O)[[email protected]](OC)C2)[[email protected]@]3([H])N(C(C([[email protected]@]4(O)[[email protected]](C)CC[[email protected]](C[[email protected]@H](/C(C)=C/C=C/C=C[[email protected]]1C)OC)([H])O4)=O)=O)CCCC3Itk inhibitors
Molecular Weight: 1030.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/10/1368