Product Name: TG101348
Synonyms: N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-4-pyrimidinyl]amino]-benzenesulfonamide Fedratinib Medchemexpress
Product Overview: A small molecule inhibitor of JAK2 (IC50 = 6 nM) and the related kinases FLT3 (IC50 = 25 nM) and RET (IC50 = 17 nM) with significantly less potent activity against JAK3 (IC50 = 169 nM); inhibits the growth of Ba/F3 cells expressing JAK2V617F or MPLW515L m
Shipping: wet ice
CAS NO: Product: PFI-3
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H36N6O3S
SMILES: CC(C)(C)NS(C1=CC=CC(NC2=NC(NC3=CC=C(OCCN4CCCC4)C=C3)=NC=C2C)=C1)(=O)=OGABA Receptor inhibitors
Molecular Weight: 524.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/12/6254.abstract
