TCS PIM-1 1
TCS PIM-1 1

TCS PIM-1 1

Product Name: TCS PIM-1 1
Synonyms: 6-(5-bromo-2-hydroxyphenyl)-1,2-dihydro-2-oxo-4-phenyl-3-pyridinecarbonitrile Pim-1 Kinase Inhibitor II Web Site:Medchemexpress
Product Overview: An ATP-competitive Pim-1 kinase inhibitor (IC50 = 50 nM) that displays selectivity over the related kinases, Pim-2 and MEK1/2 (IC50s = >20 µM)The proto-oncogene serine/threonine-protein kinases, Pim-1 and Pim-2, are enzymes involved in cytokine s
Shipping: wet ice
CAS NO: 953778-58-0 Product: MK-8998
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H11BrN2O2
SMILES: O=C1NC(C2=C(O)C=CC(Br)=C2)=CC(C3=CC=CC=C3)=C1C#NInflammation/Immunology inhibitors
Molecular Weight: 367.2
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/12/5086.abstract