SR 1555 (hydrochloride)
SR 1555 (hydrochloride)

SR 1555 (hydrochloride)

Product Name: SR 1555 (hydrochloride)
Synonyms: 1-(4-((4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-[1,1-biphenyl]-4-yl)methyl)piperazin-1-yl)ethanone,
Product Overview: A selective ligand of RORγ (IC50 = 1 μM); does not bind RORα, LXR, or FXR; acts as an inverse agonist of RORγ, inhibiting endogenous IL-17A gene expression and suppressing differentiation of TH17 cells; stimulates T regulatory develop
Shipping: wet ice
CAS NO: 141117-12-6 Product: Celgosivir (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H22F6N2O2 • HCl
SMILES: O=C(C)N(CC1)CCN1CC2=CC=C(C3=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C3)C=C2.ClProteasome inhibitors
Molecular Weight: 496.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID: