Product Name: SR 1001
Synonyms: N-(5-(N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)sulfamoyl)-4-methylthiazol-2-yl)acetamideWeb Site click
Product Overview: A synthetic ligand specific for RORα and RORγ (Kis = 172 and 111 nM, respectively) that functions as an inverse agonist; inhibits TH17 cell differentiation and IL-17A secretion in cultured splenocytes and human PBMCs at 5 μM; 25 mg/kg twic
Shipping: wet ice
CAS NO: 910462-43-0 Product: 4SC-202 (free base)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C15H13F6N3O4S2
SMILES: CC(NC1=NC(C)=C(S(NC2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)(=O)=O)S1)=OMembrane_Transporter/Ion_Channel_Compound_Library inhibitors
Molecular Weight: 477.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/2/767.abstract
