Product Name: SPD-304
Synonyms: 6,7-dimethyl-3-[[methyl[2-[methyl[[1-[3-(trifluoromethyl)phenyl]-1H-indol-3-yl]methyl]amino]ethyl]amino]methyl]-4H-1-benzopyran-4-oneMedchemexpress
Product Overview: An inhibitor of TNF-a that prevents binding to the TNFR1 (IC50 = 22 µM)Tumor necrosis factor α (TNFα) is a primary mediator of many inflammatory conditions including rheumatoid arthritis, toxic shock, and sepsis. TNFα functions as
Shipping: wet ice
CAS NO: 1375603-38-5 Product: VT-464 (R enantiomer)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C32H32F3N3O2
SMILES: CN(CCN(C)Cc1cn(c2cccc(c2)C(F)(F)F)c2ccccc12)Cc1coc2cc(C)c(C)cc2c1=OPKC inhibitors
Molecular Weight: 547.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/4/2211.abstract
