Product Name: SIRT1/2 Inhibitor IV
Synonyms: 2,3-dihydro-5-[(2-hydroxy-1-naphthalenyl)methyl]-6-phenyl-2-thioxo-4(1H)-pyrimidinone Cambinol Medchemexpress
Product Overview: A cell-permeable inhibitor of SIRT1 (IC50 = 56 µM) and SIRT2 (IC50 = 59 µM); less effectively inhibits SIRT5 (IC50 >300 µM) and has no effect on class I and II HDACs; sensitizes H460 lung cancer cells to etoposide and paclitaxel; bloc
Shipping: wet ice
CAS NO: 1141777-14-1 Product: Emixustat
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H16N2O2S
SMILES: S=C1NC(C(CC2=C(C=CC=C3)C3=CC=C2O)=C(C4=CC=CC=C4)N1)=OJAK/STAT_Compound_Library inhibitors
Molecular Weight: 360.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/12/5381.abstract
