(S)-Glycyl-H-1152 (hydrochloride)
(S)-Glycyl-H-1152 (hydrochloride)

(S)-Glycyl-H-1152 (hydrochloride)

Product Name: (S)-Glycyl-H-1152 (hydrochloride)
Synonyms: 2-amino-1-[(3S)-hexahydro-3-methyl-4-[(4-methyl-5-isoquinolinyl)sulfonyl]-1H-1,4-diazepin-1-yl]-ethanone, dihydrochloride Rho Kinase Inhibitor IVMedchemexpress
Product Overview: A selective and potent ROCK inhibitor (IC50 = 11.8 nM for ROCK-II); poorly inhibits CaMKII, protein kinase G, and Aurora A (IC50 = 2.57, 2.35, and 3.26 μM, respectively) as well as PKA or PKC (IC50 ≥ 10 μM for each)Two Rho-associated kinases (ROC
Shipping: wet ice
CAS NO: 133407-82-6 MG-132
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H24N4O3S • 2HCl
SMILES: O=S(C1=CC=CC2=C1C(C)=CN=C2)(N3CCCN(C(CN)=O)C[[email protected]@H]3C)=ONatural_Product_Library_ inhibitors
Molecular Weight: 449.4
Formulation: A solution in methanol
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/25/3352