Product Name: RAF265
Synonyms: 1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine CHIR265Medchemexpress
Product Overview: A dual inhibitor of mutant B-RafV600E and VEGFR2 (EC50s = 0.14 and 0.19 µM, respectively, in cell-based assays) that also inhibits wild-type B-Raf, PDGFR, CSF1R, RET, c-KIT, SRC, and STE20 (IC50s = 20-100 nM)RAF265 is a dual inhibitor of mutant B-Ra
Shipping: wet ice
CAS NO: 25990-60-7 Product: DL-Xylose
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H16F6N6O
SMILES: CN1C(NC2=CC=C(C(F)(F)F)C=C2)=NC3=C1C=CC(OC4=CC=NC(C5=NC=C(C(F)(F)F)N5)=C4)=C3Toxins_for_Antibody-drug_conjugates_research_Library inhibitors
Molecular Weight: 518.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/56/8/4241.abstract