Product Name: R547
Synonyms: [4-amino-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-5-pyrimidinyl](2,3-difluoro-6-methoxyphenyl)-methanone Ro 4584820Medchemexpress
Product Overview: An inhibitor of the cyclin-dependent kinases Cdk1/cyclin B, Cdk2/cyclin E, and Cdk4/cyclin D1 (Kis = 1-3 nM); inhibits tumor cell proliferation (IC50s ≤ 0.6 µM in vitro), inducing cell cycle arrest and apoptosis as well as reducing phosphorylatio
Shipping: wet ice
CAS NO: 725247-18-7 Product: XCT790
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H21F2N5O4S
SMILES: O=C(C1=C(N)N=C(NC2CCN(S(C)(=O)=O)CC2)N=C1)C3=C(F)C(F)=CC=C3OCADC Cytotoxin inhibitors
Molecular Weight: 441.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/12/7538.abstract
