Product Name: R-59-022
Synonyms: 6-[2-[4-[(4-fluorophenyl)phenylmethylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one Diacylglycerol Kinase Inhibitor IWeb Site:Medchemexpress
Product Overview: An inhibitor of DGK (IC50 = 2.8 µM), increasing DAG-dependent PKC activity; blocks vascular contraction induced by U-46619 (Item No. 16450); induces apoptosis in glioblastoma cells without being toxic to non-cancerous cells; inhibits A. thaliana DGK
Shipping: wet ice
CAS NO: 1401031-39-7 TRV130 (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H26FN3OS
SMILES: FC1=CC=C(/C(C2=CC=CC=C2)=C3CCN(CCC4=C(C)N=C(SC=C5)N5C4=O)CC3)C=C1Epigenetics_Compound_Library inhibitors
Molecular Weight: 459.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/25/3279