Product Name: Ponatinib
Synonyms: 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide AP 24534 Web Site click
Product Overview: An orally available inhibitor of native Bcr-Abl tyrosine kinase (IC50 = 0.37 nM) as well as various clinically important mutant forms including Bcr-AblT315I (IC50 = 2 nM); inhibits tumor growth in a Ba/F3 Bcr- AblT315I xenograft model of chronic myeloid l
Shipping: wet ice
CAS NO: 524684-52-4 Product: Prinaberel
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C29H27F3N6O
SMILES: CN(CC1)CCN1CC2=C(C(F)(F)F)C=C(NC(C3=CC=C(C)C(C#CC4=CN=C5N4N=CC=C5)=C3)=O)C=C2Neuronal Signaling inhibitors
Molecular Weight: 532.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/8/3601.abstract
