Product Name: Pirinixic Acid Aminothiazole
Synonyms: 2-[[4-chloro-6-[[4-(2-naphthalenyl)-2-thiazolyl]amino]-2-pyrimidinyl]thio]-octanoic acidWeb Site click
Product Overview: A dual inhibitor of mPGES-1 and 5-LO (IC50s = 0.4 and 0.2 µM, respectively); reduces the synthesis of PGE2 and LTC4 during zymosan-induced peritonitis in mice, resulting in a significantly diminished inflammatory responseMicrosomal prostaglandin E2
Shipping: wet ice
CAS NO: 606101-58-0 MK-0773
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C25H25ClN4O2S
SMILES: ClC1=NC(SC(CCCCCC)C(O)=O)=NC(NC2=NC(C3=CC=C(C=CC=C4)C4=C3)=CS2)=C1Terpenoids and Glycosides inhibitors
Molecular Weight: 513.1
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/124/21/3420
