PKR Inhibitor
PKR Inhibitor

PKR Inhibitor

Product Name: PKR Inhibitor
Synonyms: 6,8-dihydro-8-(1H-imidazol-5-ylmethylene)-7H-pyrrolo[2,3-g]benzothiazol-7-one C16 Web Site click
Product Overview: Binds the ATP-binding site of PKR and blocks autophosphorylation (IC50 = 186-210 nM); protects neuroblastoma cells against cell damage triggered by ER stress; prevents phosphorylation of FADD, preventing apoptosis; reduces phosphorylation of PKR and eIF2&
Shipping: wet ice
CAS NO: 374559-48-5 Istaroxime (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C13H8N4OS
SMILES: O=C1NC2=CC=C3C(SC=N3)=C2/C1=C/C4=CNC=N4Protein_Tyrosine_Kinase_Compound_Library inhibitors
Molecular Weight: 268.3
Formulation: A crystalline solid
Purity: ≥95%PubMed ID: