PIT-1
PIT-1

PIT-1

Product Name: PIT-1
Synonyms: N-[[(3-chloro-2-hydroxy-5-nitrophenyl)amino]thioxomethyl]-benzamideMedchemexpress
Product Overview: A selective nonphosphoinositide inhibitor that specifically disrupts PIP3/Akt PH domain binding (IC50 = 31 μM); suppresses PI3K-PDK1-Akt-dependent phosphorylation, which reduces cell viability and induces apoptosis in PTEN-deficient U87MG glioblastoma
Shipping: wet ice
CAS NO: 79455-30-4 Product: Nicaraven
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C14H10ClN3O4S
SMILES: O=C(NC(NC1=C(O)C(Cl)=CC([N+]([O-])=O)=C1)=S)C2=CC=CC=C2GlyT inhibitors
Molecular Weight: 351.8
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/10/4379.abstract