PF-573228
PF-573228

PF-573228

Product Name: PF-573228
Synonyms: 3,4-dihydro-6-[[4-[[[3-(methylsulfonyl)phenyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2(1H)-quinolinone FAK Inhibitor II Medchemexpress
Product Overview: A selective FAK inhibitor (IC50s = 4 and 30-100 nM for a purified recombinant catalytic fragment of FAK and in cultured cells, respectively) that can inhibit chemotactic and haptotactic migration of cells as well as prevent focal adhesion turnoverFocal ad
Shipping: wet ice
CAS NO: 38083-17-9 Product: Climbazole
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H20F3N5O3S
SMILES: [H]N(C1=NC(N(CC2=CC(S(=O)(C)=O)=CC=C2)[H])=C(C(F)(F)F)C=N1)C3=CC(CC4)=C(C=C3)N([H])C4=OCell Cycle_DNA Damage inhibitors
Molecular Weight: 491.5
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/56/9/4738.abstract

PF 573228

Product Name: PF 573228
Synonyms: Web Site click
Product Overview: PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β.
Shipping: wet ice
CAS NO: 212141-54-3 Product: Vatalanib (free base)
Stability: Store at +4 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H20F3N5O3S
SMILES: Mixed Lineage Kinase inhibitors
Molecular Weight: 491.49
Formulation: A crystalline solid
Purity: 0.98PubMed ID:http://aac.asm.org/content/45/6/1671.abstract