Product Name: PF-543
Synonyms: 1-[[4-[[3-methyl-5-[(phenylsulfonyl)methyl]phenoxy]methyl]phenyl]methyl]-2R-pyrrolidinemethanolWeb Site click
Product Overview: A potent inhibitor of SK1 (IC50 = 2-3.6 nM) that less effectively inhibits SK2 (IC50 = 356 nM); prevents the phosphorylation of sphingosine in cancer cells and in whole blood (EC50s = 8.4 and 27 nM, respectively); prevents sickling, hemolysis, and inflamm
Shipping: wet ice
CAS NO: 1341224-83-6 PF-4136309
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H31NO4S
SMILES: O=S(C1=CC=CC=C1)(CC2=CC(OCC3=CC=C(CN4[[email protected]@H](CO)CCC4)C=C3)=CC(C)=C2)=OTrk Receptor inhibitors
Molecular Weight: 465.6
Formulation: A crystalline solid
Purity: ≥98%PubMed ID: