Product Name: PF-04449913
Synonyms: N-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methyl-4-piperidinyl]-N-(4-cyanophenyl)-urea GlasdegibMedchemexpress.com
Product Overview: A Smo antagonist (IC50 = 5 nM); attenuates leukemia stem cell self-renewal and cell cycle progression in primary AML cells and in an in vivo Drosophila modelPF-04449913 is an orally available Hedgehog pathway inhibitor that acts by binding Smoothened (Smo
Shipping: dry ice
CAS NO: 51-30-9 Product: Isoprenaline (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H22N6O
SMILES: O=C(N[C@@H]1CCN(C)[C@@H](C2=NC(C=CC=C3)=C3N2)C1)NC4=CC=C(C#N)C=C4Dopamine Receptor inhibitors
Molecular Weight: 374.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/49/2/632.abstract
