Product Name: PD 158780
Synonyms: N4-(3-bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamineMedchemexpress.com
Product Overview: A reversible inhibitor of the auto and transphosphorylation kinase activity of the erbB receptor tyrosine kinase superfamily: EGFR (IC50 = 8 µM), erbB-2 (IC50 = 49 nM), erbB3, and erbB4 (IC50 = 52 nM); induces G1 cell cycle arrest in MCF10A breast c
Shipping: wet ice
CAS NO: 1202055-32-0 Product: NMS-P715
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C14H12BrN5
SMILES: BrC1=CC=CC(NC2=NC=NC3=C2C=C(NC)N=C3)=C1Mineralocorticoid Receptor inhibitors
Molecular Weight: 330.2
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/58/1/205.abstract
