Product Name: Olaparib
Synonyms: 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone AZD 2281 Medchemexpress
Product Overview: A potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 µM); can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and
Shipping: wet ice
CAS NO: 658084-64-1 FK866
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C24H23FN4O3
SMILES: O=C(C1CC1)N2CCN(C(C3=C(F)C=CC(CC(C4=C5C=CC=C4)=NNC5=O)=C3)=O)CC2TSH Receptor inhibitors
Molecular Weight: 434.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/8/997