Product Name: Obatoclax (mesylate)
Synonyms: 2-[2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole, monomethanesulfonate GX15-070Medchemexpress
Product Overview: An antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-XL, and Mcl-1 (KD ~500 nM); prevents interaction of these pro-survival proteins with Bax or Bak, inducing apoptosis; also induces autophagy in mouse
Shipping: wet ice
CAS NO: 481-53-8 Product: Tangeretin
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H19N3O • CH3SO3H
SMILES: CC(C=C(C)N1)=C1/C=C2C(OC)=CC(C(N3)=CC4=C3C=CC=C4)=N/2.CS(=O)(O)=OFAK inhibitors
Molecular Weight: 413.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/10/4664.abstract
