OC000459
OC000459

OC000459

Product Name: OC000459
Synonyms: 5-fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acidMedchemexpress
Product Overview: A potent, selective DP2 antagonist (Kis = 13, 3, and 4 nM for human recombinant DP2, rat recombinant DP2 receptors, and human native DP2 from Th2 cell membranes, respectivley); inhibits chemotaxis and cytokine production of human Th2 lymphocytes with IC50
Shipping: wet ice
CAS NO: 0 WEHI-539 (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C21H17FN2O2
SMILES: FC1=CC=C(N(CC(O)=O)C(C)=C2CC3=CC=C(C=CC=C4)C4=N3)C2=C1EBI2_GPR183 inhibitors
Molecular Weight: 348.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/1/1