Product Name: NVP-BKM120
Synonyms: 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-2-pyridinamine BuparlisibMedchemexpress.com
Product Overview: An orally bioavailable inhibitor of class I PI3K isoforms, potently blocking, in vitro, both p110α (IC50 = 52 nM) and p110β (IC50 = 166 nM); much less effectively inhibits the class III PI3K Vps34 and mTOR and has no effect on PI4Kβ and se
Shipping: wet ice
CAS NO: 915363-56-3 Cot inhibitor-2
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H21F3N6O2
SMILES: NC(N=C1)=CC(C(F)(F)F)=C1C2=CC(N3CCOCC3)=NC(N4CCOCC4)=N2p38 MAPK inhibitors
Molecular Weight: 410.4
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://www.bloodjournal.org/content/127/7/882