M8-B (hydrochloride)
M8-B (hydrochloride)

M8-B (hydrochloride)

Product Name: M8-B (hydrochloride)
Synonyms: N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide, monohydrochlorideWeb Site click
Product Overview: A selective antagonist of TRPM8 that blocks activation by cold, icilin, or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively); decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 knockout
Shipping: dry ice
CAS NO: 298-83-9 Product: NBT
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H24N2O3S • HCl
SMILES: COC(C=C(CN(C(C1=CC=CS1)=O)CCN)C=C2)=C2OCC3=CC=CC=C3.ClInsulin Receptor inhibitors
Molecular Weight: 433
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/48/7/2742.abstract