Product Name: Lonafarnib
Synonyms: 4-[2-[4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide SaMedchemexpress.com
Product Overview: A farnesyltransferase inhibitor that blocks the post-translational lipid modification of oncogenic Ras isoforms H-Ras, N-Ras, and K-Ras (IC50s = 1.9, 2.8, and 5.2 nM, respectively) and Rheb (IC50 = 10-100 nM); demonstrates potent dose-dependent oral activ
Shipping: wet ice
CAS NO: 1173671-63-0 Product: Rhosin
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C27H31Br2ClN4O2
SMILES: BrC1=CN=C([C@H](C2CCN(C(CC3CCN(C(N)=O)CC3)=O)CC2)C(C(Br)=CC(Cl)=C4)=C4CC5)C5=C1ALK inhibitors
Molecular Weight: 638.8
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/8/4027.abstract
