LY411575

Product Name: LY411575
Synonyms: N-[(1S)-2-[[(7S)-6,7-dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-αS-hydroxy-benzeneacetamideWeb Site:Medchemexpress
Product Overview: A cell-permeable γ-secretase inhibitor (IC50 = 0.14 nM) that has been shown to block Notch activation in vitro at 500 µM; induces apoptosis in Kaposi’s sarcoma cells, promotes intestinal goblet cell differentiation in a mouse model of c
Shipping: wet ice
CAS NO: 827022-33-3 Palbociclib (isethionate)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C26H23F2N3O4
SMILES: FC1=CC([[email protected]](O)C(N[[email protected]@H](C)C(N[[email protected]]2C(C=CC=C3)=C3C(C=CC=C4)=C4N(C)C2=O)=O)=O)=CC(F)=C1Mps1 inhibitors
Molecular Weight: 479.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/11/1386