LY2811376
LY2811376

LY2811376

Product Name: LY2811376
Synonyms: (4S)-4-[2,4-difluoro-5-(5-pyrimidinyl)phenyl]-5,6-dihydro-4-methyl-4H-1,3-thiazin-2-amineWeb Site:Medchemexpress
Product Overview: A non-peptide inhibitor of BACE1 (IC50 = 239 nM) that demonstrates ~10-fold selectivity over BACE2 and >50-fold selectivity over other aspartyl proteases; decreases Aβ in APP-overexpressing cells and transgenic animal models and reduces C99 and sA
Shipping: wet ice
CAS NO: 130-40-5 Product: Riboflavin (phosphate sodium)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C15H14F2N4S
SMILES: FC(C=C(F)C([[email protected]]1(C)CCSC(N)=N1)=C2)=C2C3=CN=CN=C3HCV inhibitors
Molecular Weight: 320.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/56/11/5916.abstract