Product Name: LY2784544
Synonyms: 3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(4-morpholinylmethyl)-imidazo[1,2-b]pyridazin-6-amineMedchemexpress
Product Overview: A potent, ATP-competitive inhibitor of JAK2 that less effectively inhibits JAK3 (IC50s = 3 and 48 nM, respectively); inhibits JAK2 containing the V617F mutation (IC50 = 20 nM); reduces the growth of Ba/F3 pro-B-cells in SCID mice without affecting erythro
Shipping: wet ice
CAS NO: 1321546-70-6 Product: (S)-(-)-5-Fluorowillardiine (hydrochloride)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H25ClFN7O
SMILES: CC1=CC(NC2=NN3C(C(CN4CCOCC4)=C2)=NC(C)=C3CC5=C(F)C=C(Cl)C=C5)=NN1ADC Linker inhibitors
Molecular Weight: 470
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/10/4673.abstract
