LEE011
LEE011

LEE011

Product Name: LEE011
Synonyms: 7-​cyclopentyl-​N,​N-​dimethyl-​2-​[[5-​(1-​piperazinyl)​-​2-​pyridinyl]​amino]​-7H-​pyrrolo[2,​3-​d]​pyrimidine-​6-​carboxamide RibociclibWeb Site click
Product Overview: A selective cyclin D1/CDK4 and cyclin D3/CDK6 inhibitor (nm IC50) that inhibits retinoblastoma protein phosphorylation, which prevents CDK-mediated G1-S phase transition, arresting the cell cycle in the G1 phase, suppressing DNA synthesis, and inhibiting
Shipping: wet ice
CAS NO: 17230-88-5 Product: Danazol
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H30N8O
SMILES: O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(C=C4)=NC=C4N5CCNCC5Polo-like Kinase PLK) inhibitors
Molecular Weight: 434.5
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/56/10/5212.abstract