LDN-212854
LDN-212854

LDN-212854

Product Name: LDN-212854
Synonyms: 5-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinolineWeb Site click
Product Overview: A selective ALK2 inhibitor (IC50 = 1.3 nM) that less potently inhibits ALK1 and ALK3 (IC50 = 2.4 and 85.8 nM, respectively) and demonstrates over 1,500-fold selectivity against the closely related activin and TGF-β type I receptors (i.e., ALK4 and AL
Shipping: wet ice
CAS NO: 453562-69-1 Motesanib
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C25H22N6
SMILES: N1(C2=CC=C(C(C=N3)=CN4C3=C(C5=C(C=CC=N6)C6=CC=C5)C=N4)C=C2)CCNCC1Dopamine Receptor inhibitors
Molecular Weight: 406.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/129/2/268