L-161,982

Product Name: L-161,982
Synonyms: N-[[4-[[3-butyl-1,5-dihydro-5-oxo-1-[2-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-4-yl]methyl][1,1-biphenyl]-2-yl]sulfonyl]-3-methyl-2-thiophenecarboxamideMedchemexpress.com
Product Overview: A potent and selective EP4 receptor antagonist (Ki = 24 nM); reverses the anti-inflammatory action of PGE2 in LPS – activated human macrophages at 100 nMProstaglandin E2 (PGE2) exerts its effects through four separate G coupled-protein receptors (EP1-4).
Shipping: wet ice
CAS NO: 142880-36-2 GM6001
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C32H29F3N4O4S2
SMILES: CCCCc1nn(c(=O)n1Cc1ccc(cc1)c1ccccc1S(=O)(=O)NC(=O)c1sccc1C)c1ccccc1C(F)(F)FCRM1 inhibitors
Molecular Weight: 654.2
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://www.bloodjournal.org/content/127/6/663