Ku-0063794
Ku-0063794

Ku-0063794

Product Name: Ku-0063794
Synonyms: rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxy-benzenemethanolWeb Site:Medchemexpress
Product Overview: A cell-permeable, selective dual inhibitor of mTORC1 and mTORC2 (IC50 = 10 nM); not affect the activity of 76 other protein kinases or seven lipid kinases, including PI3Ks; induces G1-cell cycle arrest and autophagy; inhibits tumor growth in a xenograft m
Shipping: wet ice
CAS NO: 1228585-88-3 GS-9620
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C25H31N5O4
SMILES: OCC1=C(OC)C=CC(C2=CC=C3C(N=C(N4C[[email protected]@H](C)O[[email protected]@H](C)C4)N=C3N5CCOCC5)=N2)=C1TSH Receptor inhibitors
Molecular Weight: 465.5
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/116/21/238