JAK Inhibitor I
JAK Inhibitor I

JAK Inhibitor I

Product Name: JAK Inhibitor I
Synonyms: 2-(1,1-dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one CMP 6 Web Site:Medchemexpress
Product Overview: A pyridine-containing tetracycle that interferes with JAK kinase activity interacting within the ATP-binding cleft (IC50s = 15, 1, and 5 nM for JAK1, 2, and 3, respectively); block IL-2 and IL-4-dependent proliferation of mouse T-cell lymphoma cells (IC50
Shipping: wet ice
CAS NO: 698394-73-9 Vercirnon
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H16FN3O
SMILES: O=C1NC=CC2=C1C(C=C(F)C=C3)=C3C4=C2NC(C(C)(C)C)=N4Membrane Transporter_Ion Channel inhibitors
Molecular Weight: 309.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/7/908