IPI-145

Product Name: IPI-145
Synonyms: 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone Duvelisib Web Site click
Product Overview: A potent, selective, and orally bioavailable inhibitor of PI3Kγ and PI3Kδ (IC50s = 0.24 and 50 nM, respectively); has profound effects in collagen-induced and adjuvant-induced arthritis, ovalbumin-induced asthma, and systemic lupus erythematos
Shipping: wet ice
CAS NO: 1190308-01-0 PSI-7976
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C22H17ClN6O
SMILES: C[[email protected]@H](C1=CC(C=CC=C2Cl)=C2C(N1C3=CC=CC=C3)=O)NC4=C5C(N=CN5)=NC=N4Histone Acetyltransferase inhibitors
Molecular Weight: 416.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://www.bloodjournal.org/content/127/10/1219