Product Name: IOX2
Synonyms: N-[[1,2-dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]-glycineWeb Site:Medchemexpress
Product Overview: Potent, cell permeable inhibitor of PHD2 (IC50 = 21 nM) with over 100-fold selectivity compared to inhibition of JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH (IC50s > 100 μM); inhibits HIF-1α hydroxylation in RCC4 cells at 50 μMH
Shipping: wet ice
CAS NO: 1357171-62-0 Product: ML228
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C19H16N2O5
SMILES: OC(C1=CC=CC=C1N2CC3=CC=CC=C3)=C(C(NCC(O)=O)=O)C2=OCOMT inhibitors
Molecular Weight: 352.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/8/3528.abstract