Hedgehog Antagonist VIII
Hedgehog Antagonist VIII

Hedgehog Antagonist VIII

Product Name: Hedgehog Antagonist VIII
Synonyms: N-[4-chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]-urea Hh Antagonist VIIIMedchemexpress.com
Product Overview: A cell-permeable quinazolinyl-urea compound that has been shown to inhibit Gli transcription activity (IC50 = 70 nM)Hedgehog (Hh) proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of Smoothened. In v
Shipping: wet ice
CAS NO: 577-11-7 Product: Docusate (Sodium)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C23H15ClF4N4O2
SMILES: O=C1C2=CC=CC=C2N=C(CNC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)N1C4=CC=C(F)C=C4URAT1 inhibitors
Molecular Weight: 490.8
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/56/6/3011.abstract