Product Name: Halofuginone (hydrochloride)
Synonyms: 7-bromo-6-chloro-3-[3-[(2R,3S)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4(3H)-quinazolinone, monohydrochlorideMedchemexpress.com
Product Overview: A halogenated derivative of febrifugine that down-regulates Smad3, blocking TGF-β signaling relevant to fibrosis and tumor progression in a variety of different models; competitively inhibits prolyl-tRNA synthetase (Ki = 18.3 nM), preventing the dif
Shipping: wet ice
CAS NO: 1082949-68-5 Product: LY-2584702 (tosylate salt)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C16H17BrClN3O3 • HCl
SMILES: BrC1=C(Cl)C=C2C(N=CN(CC(C[C@H]3NCCC[C@@H]3O)=O)C2=O)=C1.ClMps1 inhibitors
Molecular Weight: 451.1
Formulation: A crystalline solid
Purity: ≥95%PubMed ID:http://aac.asm.org/content/57/10/5087.abstract