H-89 (hydrochloride)
H-89 (hydrochloride)

H-89 (hydrochloride)

Product Name: H-89 (hydrochloride)
Synonyms: N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]5-isoquinolinesulfonamide, dihydrochloride 5-Isoquinolinesulfonamide Web Site:Medchemexpress
Product Overview: A potent, non-selective inhibitor of PKA with an IC50 value of 0.14 µM (Ki = 48 nM) that is widely used to disrupt PKA signaling; inhibits S6K1, MSK1, ROCK-II, PKBa, and MAPKAP-K1b with IC50 values of 0.08, 0.12, 0.27, 2.6, and 2.8 µM, respec
Shipping: wet ice
CAS NO: 146368-11-8 Product: CY5
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H20BrN3O2S • 2HCl
SMILES: O=S(C1=CC=CC2=CN=CC=C21)(NCCNC/C=C/C3=CC=C(Br)C=C3)=O.Cl.ClItk inhibitors
Molecular Weight: 519.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/56/3/1548.abstract