Product Name: GW 2580
Synonyms: 5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamineMedchemexpress
Product Overview: A selective inhibitor of cFMS kinase (IC50 = 0.03 μM) that prevents CSF-1-induced monocyte growth with an IC50 value of 0.14 μM; at 75-100 mg/kg, inhibits joint connective tissue and bone degradation in mouse models of arthritiscFMS kinase is the ce
Shipping: wet ice
CAS NO: 1597403-47-8 Product: ISRIB (trans-isomer)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C20H22N4O3
SMILES: NC1=NC(N)=C(CC2=CC(OC)=C(OCC3=CC=C(OC)C=C3)C=C2)C=N1CDK inhibitors
Molecular Weight: 366.4
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/57/10/4816.abstract