Product Name: GSK4112
Synonyms: N-[(4-chlorophenyl)methyl]-N-[(5-nitro-2-thienyl)methyl]-glycine, 1,1-dimethylethyl esterWeb Site:Medchemexpress
Product Overview: A synthetic agonist for REV-ERBα (EC50 = 0.4 μM) that mimics the action of heme; at 10 μM inhibits the expression of the circadian target gene bmal1 and reduces glucose output by 30% in mouse primary hepatocytes by repressing the expression of
Shipping: wet ice
CAS NO: 232931-57-6 Product: SJG-136
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C18H21ClN2O4S
SMILES: ClC(C=C1)=CC=C1CN(CC(OC(C)(C)C)=O)CC2=CC=C([N+]([O-])=O)S2Salt-inducible Kinase SIK) inhibitors
Molecular Weight: 396.9
Formulation: A crystalline solid
Purity: ≥98%PubMed ID: