GNE-0877
GNE-0877

GNE-0877

Product Name: GNE-0877
Synonyms: α,α,3-trimethyl-4-[[4-(methylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1H-pyrazole-1-acetonitrileWeb Site:Medchemexpress
Product Overview: A selective, brain-penetrable LRRK2 inhibitor (Ki = 0.7 nM); inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson’s disease mutation (IC50 = 3 nM in vivo)Leucine-rich repeat kinas
Shipping: wet ice
CAS NO: 106612-94-6 Product: GLP-1(7-37)
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C14H16F3N7
SMILES: CNC1=C(C(F)(F)F)C=NC(NC2=CN(C(C)(C#N)C)N=C2C)=N1Protease-Activated Receptor PAR) inhibitors
Molecular Weight: 339.3
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/54/9/3998.abstract