EPZ005687
EPZ005687

EPZ005687

Product Name: EPZ005687
Synonyms: 1-cyclopentyl-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-6-[4-(4-morpholinylmethyl)phenyl]-1H-indazole-4-carboxamideWeb Site:Medchemexpress
Product Overview: A potent, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 24 nM), the enzymatic subunit of PRC2; blocks trimethylation of the PRC2 target H3K27 (IC50 = 80 nM), decreasing the proliferation of lymphoma cells carrying mutant, but not wild-type
Shipping: wet ice
CAS NO: 328023-11-6 Product: Rbin-1
Stability: Store at -20 degrees; shelf life 730 days maximum after production
Molecular Formula: C32H37N5O3
SMILES: O=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C3=CC=C(CN4CCOCC4)C=C3)=CC5=C2C=NN5C6CCCC6Angiotensin Receptor inhibitors
Molecular Weight: 539.7
Formulation: A crystalline solid
Purity: ≥98%PubMed ID:http://aac.asm.org/content/55/2/925.abstract